Malignancy induced haemophagocytosis of leukaemic blasts by macrophages and transformation into a multinucleated giant cells

Prachi; Gaurav Sharma; Suparno Chakrabarti

Abstract

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Malignancy induced haemophagocytosis of leukaemic blasts by macrophages and transformation into a multinucleated giant cells

Prachi*, Gaurav Sharma and Suparno Chakrabarti

Published: 27 July, 2021 | Volume 5 - Issue 1 | Pages: 007-007

Haemophagocytosis is a dysregulated immune condition characterised by both inflammation and uncontrolled activation of macrophages and T-cells, which causes aberrant cytokine release, leading to cytokine storm [1] it can be primary or secondary, depending upon the etiology.

Read Full Article HTML DOI: 10.29328/journal.jcmei.1001023 Cite this Article Read Full Article PDF

References

1. Janka GE. Hemophagocytic syndromes. Blood Rev. 2007; 21: 245–253. PubMed: https://pubmed.ncbi.nlm.nih.gov/17590250/

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