Abstract

Research Article

Assessment of the Quality of Life in Patients Undergoing Radical Cystectomy with Urinary Diversion

Mohamed Ali Mikou, Ilyas Soufiani, Mohamed Bakouch, Hamza El-Abidi, Idriss Ziani, Imad Boualaoui, Ahmed Ibrahimi and Yassine Nouini

Published: 24 June, 2026 | Volume 10 - Issue 1 | Pages: 44-49

Radical cystectomy with urinary diversion is the standard treatment for muscle-invasive bladder cancer. The impact of the type of urinary diversion on quality of life (QoL) remains debated. This cross-sectional study assessed QoL in 57 patients who underwent radical cystectomy between 2014 and 2022 at two urology departments in Rabat, Morocco, using the Bladder Cancer Index (BCI), the SF-36, and the Body Image Scale (BIS). Multiple linear regression identified socioeconomic status, body image perception, urinary discomfort, and comorbidities as the main determinants of QoL, with the type of urinary diversion playing an indirect role mediated through these factors. These findings underscore the need for a multidimensional approach when evaluating and optimizing QoL outcomes after radical cystectomy.

Read Full Article HTML DOI: 10.29328/journal.jcmei.1001048 Cite this Article Read Full Article PDF

Keywords:

Radical cystectomy; Urinary diversion; Quality of life; Bladder cancer; Body image; Socioeconomic status

References

  1. World Health Organization. WHOQOL – Measuring Quality of Life. Available from: https:// who.int/tools/whoqol
  2. Coates A, Porzsolt F, Osoba D. Quality of life in oncology practice: Prognostic value of EORTC QLQ-C30 scores in patients with advanced malignancy. Eur J Cancer. 1997;33(7):1025–1030. Available from: https://doi.org/10.1016/s0959-8049(97)00049-x
  3. Roychowdhury DF, Hayden A, Liepa AM. Health-related quality-of-life parameters as independent prognostic factors in advanced or metastatic bladder cancer. J Clin Oncol. 2003;21(4):673–678. Available from: https://doi.org/10.1200/jco.2003.04.166
  4. Gilbert SM, Dunn RL, Hollenbeck BK, Montie JE, Lee CT, Wood DP, et al. Development and validation of the Bladder Cancer Index: a comprehensive, disease-specific measure of health-related quality of life in patients with localized bladder cancer. J Urol. 2010;183(5):1764–1770. Available from: https://doi.org/10.1016/j.juro.2010.01.013
  5. Ziouziou I, Touzani MA, Karmouni T. Arabic translation and linguistic validation of the Bladder Cancer Index questionnaire. Afr J Urol. 2018;24(2):104–107.
  6. Brazier JE, Harper R, Jones NM, O'Cathain A, Thomas KJ, Usherwood T, et al. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992;305(6846):160–164. Available from:https://doi.org/10.1136/bmj.305.6846.160
  7. Hopwood P, Fletcher I, Lee A, Al Ghazal S. A body image scale for use with cancer patients. Eur J Cancer. 2001;37(2):189–197. Available from: https://doi.org/10.1016/s0959-8049(00)00353-1
  8. Goldberg H, Baniel J, Mano R, Rotlevy G, Kedar D, Yossepowitch O. Orthotopic neobladder vs. ileal conduit urinary diversion: a long-term quality-of-life comparison. Urol Oncol. 2016;34(3):121.e1–121.e7. Available from:https://doi.org/10.1016/j.urolonc.2015.10.006
  9. Gellhaus PT, Cary C, Kaimakliotis HZ, Johnson CS, Weiner M, Koch MO, et al. Long-term health-related quality of life outcomes following radical cystectomy. Urology. 2017;106:82–86. Available from: https://doi.org/10.1016/j.urology.2017.03.053
  10. Héver NV, Péntek M, Balló A, Gulácsi L, Baji P, Brodszky V, et al. Health-related quality of life in patients with bladder cancer: a cross-sectional survey and validation study of the Hungarian version of the Bladder Cancer Index. Pathol Oncol Res. 2015;21(3):619–627. Available from: https://doi.org/10.1007/s12253-014-9866-7
  11. Osawa T, Wei JT, Abe T, Honda M, Yamada S, Furumido J, et al. Health-related quality of life in Japanese patients with bladder cancer measured by a newly developed Japanese version of the Bladder Cancer Index. Int J Clin Oncol. 2020;25(12):2090–2098. Available from: https://doi.org/10.1007/s10147-020-01770-2
  12. Clements MB, Atkinson TM, Dalbagni GM, Li Y, Vickers AJ, Herr HW, et al. Health-related quality of life for patients undergoing radical cystectomy: results of a large prospective cohort. Eur Urol. 2022;81(3):294–304. Available from: https://doi.org/10.1016/j.eururo.2021.09.018
  13. Huang Y, Pan X, Zhou Q, Huang H, Li L, Cui X, et al. Quality-of-life outcomes and unmet needs between ileal conduit and orthotopic ileal neobladder after radical cystectomy in a Chinese population: a 2to-1 matched-pair analysis. BMC Urol. 2015;15(1):117. Available from: https://doi.org/10.1186/s12894-015-0113-7
  14. Herrel L, Umarji R, Lee C. Sexual function changes in bladder cancer patients undergoing cystectomy. J Urol. 2015;193(4S):e520.
  15. Min C, Qiang L, Feifan W. Sexual function in males after radical cystectomy. J Sex Med. 2018;15(Suppl 3):S293.
  16. Hedgepeth RC, Gilbert SM, He C, Lee CT, Wood DP. Body image and bladder cancer-specific quality of life in patients with ileal conduit and neobladder urinary diversions. Urology. 2010;76(3):671–675. Available from: https://doi.org/10.1016/j.urology.2010.01.087
  17. Shi H, Yu H, Bellmunt J, et al. Comparison of health-related quality of life (HRQoL) between ileal conduit diversion and orthotopic neobladder based on validated questionnaires: a systematic review and meta-analysis. Qual Life Res. 2018;27(11):2759–2775. Available from: https://doi.org/10.1007/s11136-018-1902-8
  18. Nayir T, Uskun E, Yürekli MV, Leow JJ, Chen X, Guo C, et al. Does body image affect quality of life? A population-based study. PLoS ONE. 2016;11(9):e0163290. Available from: https://doi.org/10.1007/s11136-018-1902-8
  19. Chow KM, Chan CWH, Leung AWY, Wong MMH, Choi KC. Relationship between body image and health-related quality of life in Chinese cancer survivors during the transitional cancer survivorship period. Psychooncology. 2019 Feb;28(2):324-328. Available from: https://doi.org/10.1002/pon.4943
  20. Teo I, Cheung YB, Lim TYK, Namuduri RP, Long V, et al. The relationship between symptom prevalence, body image, and quality of life in Asian gynecologic cancer patients. Psychooncology. 2018 Jan;27(1):69-74. Available from: https://doi.org/10.1002/pon.4457
  21. Henry M, Ho A, Lambert SD, Carnevale FA, Greenfield B, MacDonald C, et al. Looking beyond disfigurement: the experience of patients with head and neck cancer. J Palliat Care. 2014;30(1):5–15.
  22. Rhoten BA, Murphy B, Ridner SH. Body image in patients with head and neck cancer: a review of the literature. Oral Oncol. 2013;49(8):753–760. Available from: https://doi.org/10.1016/j.oraloncology.2013.04.005

Figures:

Similar Articles

  • Obstructive Pyelonephritis Due to Postoperative Ureteral Stricture: A Case Report
    Ayoub Mamad*, Mohammed Amine Elafari, Mohammed Amine Bibat, Midaoui Moncef, Amine Slaoui, Tarik Karmouni, Abdelatif Koutani and Khalid Elkhader Ayoub Mamad*,Mohammed Amine Elafari,Mohammed Amine Bibat,Midaoui Moncef,Amine Slaoui,Tarik Karmouni,Abdelatif Koutani,Khalid Elkhader. Obstructive Pyelonephritis Due to Postoperative Ureteral Stricture: A Case Report. . 2026 doi: 10.29328/journal.jcmei.1001039; 10: 003-005
  • Adult Bladder Exstrophy with Premalignant Changes Following Failed Reconstruction: A Case Report
    Mohammed Amine Elafari*, Mamad Ayoub, Mohamed Amine Zaki, Mohammed Amine Bibat, Amine Slaoui, Tarik Karmouni, Abdelatif Koutani and Khalid Elkhader Mohammed Amine Elafari*,Mamad Ayoub,Mohamed Amine Zaki,Mohammed Amine Bibat,Amine Slaoui,Tarik Karmouni,Abdelatif Koutani,Khalid Elkhader. Adult Bladder Exstrophy with Premalignant Changes Following Failed Reconstruction: A Case Report. . 2026 doi: 10.29328/journal.jcmei.1001044; 10: 020-023
  • Assessment of the Quality of Life in Patients Undergoing Radical Cystectomy with Urinary Diversion
    Mohamed Ali Mikou, Ilyas Soufiani, Mohamed Bakouch, Hamza El-Abidi, Idriss Ziani, Imad Boualaoui, Ahmed Ibrahimi and Yassine Nouini Mohamed Ali Mikou,Ilyas Soufiani,Mohamed Bakouch,Hamza El-Abidi,Idriss Ziani,Imad Boualaoui,Ahmed Ibrahimi,Yassine Nouini. Assessment of the Quality of Life in Patients Undergoing Radical Cystectomy with Urinary Diversion. . 2026 doi: 10.29328/journal.jcmei.1001048; 10: 44-49

Recently Viewed

Read More

Most Viewed

Read More

Help ?